Fig. 1 · Structure
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8-Mercaptoguanosine
Immunoadjuvant
8-Mercaptoguanosine is an immunoadjuvant that enhances the in vivo antibody response to T-cell-independent antigens, specifically TNP-Ficoll. This compound significantly stimulates the production of IgG1, IgG2, and IgG3 antibodies while having no impact on IgM levels. Additionally, 8-Mercaptoguanosine boosts immune responses to weak antigens, such as pneumococcal polysaccharide, and can restore antibody responses in immunodeficient xid mice lacking reactivity to TNP-Ficoll. Its unique properties make it a valuable tool for research in immunology and vaccine development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 26001-38-7 |
| Applications | Immunoadjuvant |
| Formula | C10H13N5O5S |
| Molecular Weight | 315.31 |
| Synonyms | 8-Thioguanosine |
| SMILES | NC(NC1=O)=NC2=C1NC(N2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)=S |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.