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8-NBD-cGMP

Fluorescence Activator

8-NBD-cGMP is a fluorescent analog of cyclic guanosine monophosphate that serves as a potent fluorescence activator for cGMP-dependent protein kinase isozymes Iα and Iβ. While it displays minimal fluorescence in aqueous environments, it exhibits strong fluorescence in hydrophobic settings, making it an invaluable tool for investigating protein interactions and dynamics. This compound is essential for research applications involving signal transduction pathways mediated by cGMP.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Activator
CAS Number	115993-88-9
Applications	Fluorescence Activator
Formula	C₁₈H₁₈N₉O₁₀PS
Molecular Weight	583.43
SMILES	O=C1C(N=C(SCCNC2=CC=C([N+]([O-])=O)C3=NON=C32)N4[C@H]5[C@H](O)[C@H](O6)[C@@H](COP6(O)=O)O5)=C4N=C(N)N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.