8-OH-DPAT

Name: 8-OH-DPAT
Brand: Adooq Bioscience
SKU: A19261
Rating: 5 (288 reviews)

Catalog No.: A19261

5-HT agonist

8-OH-DPAT is a potent and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50 <5).

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Grouped product items
Size	Price	Stock
5mg	$40.00	In stock
10mg	$65.00	In stock
25mg	$140.00	In stock
50mg	$225.00	In stock
100mg	$405.00	In stock
*10mM 1mL in DMSO**	$470.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description

8-OH-DPAT is a potent and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC50, 5.42), 5-HT (pIC50 <5).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A19261
Formula	C16H25NO
Molecular Weight	247.38
CAS Number	78950-78-4
SMILES	OC1=C2CC(N(CCC)CCC)CCC2=CC=C1
Synonyms	8-Hydroxy-DPAT
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	46 mg/mL (185.94 mM)
	Water	Insoluble
	Ethanol	46 mg/mL (185.94 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	40.42 mL	202.12 mL	404.24 mL
0.5 mM	8.08 mL	40.42 mL	80.85 mL
1 mM	4.04 mL	20.21 mL	40.42 mL
5 mM	0.81 mL	4.04 mL	8.08 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂