Fig. 1 · Structure
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8-(p-Sulfophenyl)theophylline
Adenosine A2B Receptor Antagonist
8-(p-Sulfophenyl)theophylline is an adenosine A2B receptor antagonist, exhibiting a Ki value of 1330 nM for the human recombinant A2B receptor. This compound serves as a valuable tool in the study of adenosine signaling pathways and their implications in various physiological and pathological processes. Its selective inhibition of the A2B receptor allows for exploration of therapeutic targets in areas such as inflammation, cancer, and cardiovascular diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 80206-91-3 |
| Applications | Adenosine A2B Receptor Antagonist |
| Formula | C13H12N4O5S |
| Molecular Weight | 336.32 |
| Synonyms | 8-SPT; 8-pSPT |
| SMILES | O=C1C=2NC(=NC2N(C(=O)N1C)C)C=3C=CC(=CC3)S(=O)(=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.