Fig. 1 · Structure
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(±)-8-Prenylnaringenin (Racemic 8-Prenylnaringenin)
Phytoestrogen
(±)-8-Prenylnaringenin is a potent phytoestrogen that acts as a selective estrogen receptor modulator (SERM) targeting estrogen receptors ERα and ERβ, with IC50 values of 57 nM and 68 nM, respectively. This naturally occurring prenylated flavonoid demonstrates significant anticancer properties and is valuable in osteoporosis research. Its ability to selectively modulate estrogen receptor activity makes it a useful tool for investigating hormone-related pathways and potential therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 68682-02-0 |
| Applications | Phytoestrogen |
| Formula | C20H20O5 |
| Molecular Weight | 340.37 |
| SMILES | O=C1CC(OC2=C(C(O)=CC(O)=C21)C/C=C(C)\C)C3=CC=C(C=C3)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.