A-1331852

Catalog No.: A16190

BCL-XL inhibitor

A-1331852

A-1331852 Chemical Structure

CAS NO. 1430844-80-6

A-1331852 is a potent and selective BCL-XL inhibitor. BCL-XL is the major antiapoptotic survival protein and may be a novel therapeutic target in CML.

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$200.00
50 mg
$670.00
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Biological Activity

A-1331852 is a potent and selective BCL-XL inhibitor. BCL-XL is the major antiapoptotic survival protein and may be a novel therapeutic target in CML.
Targets
Bcl-xL Bcl-w Bcl-2 Mcl-1
<0.01 nM(Ki)4 nM(Ki)6 nM(Ki)142 nM(Ki)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.18 mL 75.89 mL 151.79 mL
0.5 mM 3.04 mL 15.18 mL 30.36 mL
1 mM 1.52 mL 7.59 mL 15.18 mL
5 mM 0.3 mL 1.52 mL 3.04 mL

*The above data is based on the productmolecular weight 658.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16190
Actions Inhibitor
M. Wt 658.82
Formula C38H38N6O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1430844-80-6
Synonyms A 1331852, A1331852
SMILES CC1=C(C=NN1CC23CC4CC(C2)CC(C4)C3)C5=C(N=C(C=C5)N6CCC7=CC=CC(=C7C6)C(=O)NC8=NC9=CC=CC=C9S8)C(=O)O

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