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A-134974

Adenosine Kinase Inhibitor

A-134974 is a highly selective inhibitor of adenosine kinase, with an IC50 of 60 pM. This compound enhances endogenous adenosine signaling in the spinal cord, providing effective relief from neuropathic pain while avoiding movement disorders. A-134974 is suitable for research focused on the mechanisms and treatments of neuropathic pain.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	186141-75-3
Applications	Adenosine Kinase Inhibitor
Formula	C₁₁H₁₄IN₅O₂
Molecular Weight	375.17
SMILES	O[C@H]1[C@@H](C[C@@H]([C@H]1O)N)N2C3=NC=NC(N)=C3C(I)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.