Biological Activity
A 286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction with IC50 valueof 44 and 35 nM in LFA-1/ICAM-1 binding and LFA-1-mediated cell adhesion, respectively.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.05 mL | 110.24 mL | 220.48 mL |
0.5 mM | 4.41 mL | 22.05 mL | 44.1 mL |
1 mM | 2.2 mL | 11.02 mL | 22.05 mL |
5 mM | 0.44 mL | 2.2 mL | 4.41 mL |
*The above data is based on the productmolecular weight 453.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A17211 |
---|---|
Actions | Inhibitor |
M. Wt | 453.55 |
Formula | C24H27N3O4S |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 280749-17-9 |
Synonyms | A286982, A-286982 |
SMILES | CC(C)C1=CC=CC=C1SC2=C(C=C(C=C2)/C=C/C(=O)N3CCN(CC3)C(=O)C)[N+](=O)[O-] |
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