A-412997

Catalog No.: A60176
Dopamine D4 Receptor Agonist
A-412997 is a selective agonist of the Dopamine D4 receptor, exhibiting Ki values of 12 nM for rat and 7.9 nM for human receptors. This compound has been demonstrated to enhance short-term memory and cognitive functions in rodent models, making it a valuable tool for research into psychiatric disorders and cognitive enhancement. Its specificity and potency facilitate studies on the Dopamine D4 receptor's role in neurobiology and medicine.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionA-412997 is a selective agonist of the Dopamine D4 receptor, exhibiting Ki values of 12 nM for rat and 7.9 nM for human receptors. This compound has been demonstrated to enhance short-term memory and cognitive functions in rodent models, making it a valuable tool for research into psychiatric disorders and cognitive enhancement. Its specificity and potency facilitate studies on the Dopamine D4 receptor's role in neurobiology and medicine.
Product Information
Catalog NumA60176
FormulaC19H23N3O
Molecular Weight309.41
CAS Number630116-49-3
SMILESO=C(NC1=CC=CC(C)=C1)CN2CCC(C3=NC=CC=C3)CC2
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