Fig. 1 · Structure
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A-420983
Lck Inhibitor
A-420983 is a potent, orally active inhibitor of Lck, a key tyrosine kinase involved in T-cell signaling and immune responses. This compound exhibits significant activity in modulating T-cell activation and has applications in research studies related to delayed-type hypersensitivity and organ transplant rejection. Its efficacy makes it a valuable tool for investigating immune-related processes and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 330789-03-2 |
| Applications | Lck Inhibitor |
| Formula | C33H39N9O2 |
| Molecular Weight | 593.72 |
| SMILES | O=C(C(N1C)=CC2=C1C=CC=C2)NC3=CC=C(C4=NN([C@H]5CC[C@H](N6CCN(C)CC6)CC5)C7=NC=NC(N)=C74)C=C3OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.