A-620223 succinate is a potent inhibitor of poly(ADP-ribose) polymerase (PARP), targeting the PARP-1 enzyme with a Ki value of 8 nM and an EC50 value of 3 nM in cellular assays. Its excellent selectivity and bioavailability make it an invaluable tool for cancer research, enabling investigations into DNA repair mechanisms and potential therapeutic strategies. This compound is particularly useful in studies focused on the efficacy of PARP inhibition in various cancer models.
A-620223 succinate is a potent inhibitor of poly(ADP-ribose) polymerase (PARP), targeting the PARP-1 enzyme with a Ki value of 8 nM and an EC50 value of 3 nM in cellular assays. Its excellent selectivity and bioavailability make it an invaluable tool for cancer research, enabling investigations into DNA repair mechanisms and potential therapeutic strategies. This compound is particularly useful in studies focused on the efficacy of PARP inhibition in various cancer models.
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