A-674563 hydrochloride

Catalog No.: A25907
Akt1 Inhibitor
A-674563 hydrochloride is a selective inhibitor of Akt1, exhibiting a Ki value of 11 nM. This compound effectively disrupts Akt1 signaling, making it a valuable tool for investigating the role of this kinase in cellular processes such as metabolism, survival, and proliferation. A-674563 hydrochloride is suitable for use in various research applications, including cancer research and studies focused on metabolic disorders.
Grouped product items
Size Price Stock Qty
1mg
$60.00
In stock
2mg
$90.00
In stock
5mg
$115.00
In stock
10mg
$185.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionA-674563 hydrochloride is a selective inhibitor of Akt1, exhibiting a Ki value of 11 nM. This compound effectively disrupts Akt1 signaling, making it a valuable tool for investigating the role of this kinase in cellular processes such as metabolism, survival, and proliferation. A-674563 hydrochloride is suitable for use in various research applications, including cancer research and studies focused on metabolic disorders.
Product Information
Catalog NumA25907
FormulaC22H23ClN4O
Molecular Weight394.90
CAS Number2070009-66-2
SMILESN[C@@H](CC1=CC=CC=C1)COC2=CC(C3=CC4=C(C=C3)NN=C4C)=CN=C2.[H]Cl
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