Fig. 1 · Structure
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A 844606
α4β2 nAChR Agonist
A 844606 is a highly selective agonist of the α4β2 nicotinic acetylcholine receptor (nAChR), demonstrating potent activation of this target. Its significant biological activity makes it a valuable tool for investigating neurodegenerative and psychiatric conditions, including schizophrenia, Huntington's disease, Alzheimer's disease, and Parkinson's disease. Researchers can utilize A 844606 to explore the role of α4β2 nAChR in these disorders and to assess potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 861119-08-6 |
| Applications | α4β2 nAChR Agonist |
| Formula | C20H20N2O2 |
| Molecular Weight | 320.39 |
| SMILES | O=C1C2=C(OC3=CC=C(N4CC5CN(CC5C4)C)C=C31)C=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.