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A-849529

ABT-869 Metabolite

A-849529 is an acid metabolite of ABT-869, a potent, orally active multi-target inhibitor of the vascular endothelial growth factor receptor (VEGFR) and platelet-derived growth factor receptor (PDGFR) families. This compound retains significant biological activity, making it valuable for research focused on angiogenesis and tumor growth inhibition. A-849529 is suitable for studies investigating the mechanisms of action of VEGFR and PDGFR inhibitors in various cancer models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	819058-88-3
Applications	ABT-869 Metabolite
Formula	C₂₁H₁₆FN₅O₃
Molecular Weight	405.38
SMILES	O=C(C1=CC=C(C(NC(NC2=CC=C(C3=C4C(N)=NNC4=CC=C3)C=C2)=O)=C1)F)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.