Fig. 1 · Structure
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A-908292
ACC2 Inhibitor
A-908292 is a selective inhibitor of acetyl-CoA carboxylase 2 (ACC2), exhibiting an IC50 of 23 nM against human ACC2. This compound is instrumental for studies related to fatty acid metabolism and has applications in metabolic engineering. Additionally, A-908292 features an alkyne group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) for use in click chemistry methodologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 903886-95-3 |
| Applications | ACC2 Inhibitor |
| Formula | C18H20N2O4S |
| Molecular Weight | 360.43 |
| SMILES | COC(N[C@@H](C)C#CC1=CN=C(S1)OC2=CC=C(C=C2)OC(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.