Fig. 1 · Structure
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α-Angelica lactone
Chemopreventative Agent
α-Angelica lactone is a naturally occurring chemopreventative agent with notable anticarcinogenic properties. It serves as a vinylogous nucleophile capable of producing chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and facilitates electrophilic trapping at the γ-carbon. This compound exhibits strong chemoprotective effects through the selective enhancement of detoxification enzymes, particularly glutathione-S-transferase (GST) and UDP-glucuronosyltransferase (UGT), making it valuable for research in cancer prevention and detoxification pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 591-12-8 |
| Applications | Chemopreventative Agent |
| Formula | C5H6O2 |
| Molecular Weight | 98.10 |
| SMILES | O=C1OC(C)=CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.