Fig. 1 · Structure
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α-Demethylnaproxen
Nabumetone Metabolite
α-Demethylnaproxen is the principal metabolite of Nabumetone, an orally active selective cyclooxygenase-2 (COX-2) inhibitor known for its anti-inflammatory properties. This compound plays a significant role in understanding the pharmacokinetics and biological effects of Nabumetone. Research applications include studies on inflammation, pain modulation, and the evaluation of COX-2 inhibition in various biological systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 23981-47-7 |
| Applications | Nabumetone Metabolite |
| Formula | C13H12O3 |
| Molecular Weight | 216.24 |
| SMILES | O=C(O)CC1=CC=C2C=C(OC)C=CC2=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.