Fig. 1 · Structure
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α-Galactosylceramide
NKT Cell Agonist
α-Galactosylceramide is a synthetic glycolipid that serves as a potent agonist for natural killer T (NKT) cells, targeting the CD1d molecule. Through its interaction with CD1d, α-Galactosylceramide activates NKT cells, leading to robust immunostimulatory and antitumoral effects. This compound is widely utilized in research applications focusing on immune modulation, cancer therapy, and the mechanistic understanding of NKT cell biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 158021-47-7 |
| Applications | NKT Cell Agonist |
| Formula | C50H99NO9 |
| Molecular Weight | 858.34 |
| Synonyms | α-GalCer; KRN7000 |
| SMILES | CCCCCCCCCCCCCCCCCCCCCCCCCC(N[C@@H](CO[C@@H]1[C@@H]([C@H]([C@H]([C@@H](CO)O1)O)O)O)[C@H](O)[C@H](O)CCCCCCCCCCCCCC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.