α-Helical CRF(9-41) is a competitive antagonist of the corticotropin-releasing factor receptor 2 (CRF₂) with a K\_B of approximately 100 nM. It also acts as a partial agonist at the CRF₁ receptor, with an EC₅₀ of 140 nM. This dual activity makes it a useful tool for studying CRF receptor signaling and stress-related physiological responses.
α-Helical CRF(9-41) is a competitive antagonist of the corticotropin-releasing factor receptor 2 (CRF₂) with a K\_B of approximately 100 nM. It also acts as a partial agonist at the CRF₁ receptor, with an EC₅₀ of 140 nM. This dual activity makes it a useful tool for studying CRF receptor signaling and stress-related physiological responses.
Product Information
Catalog Num
A24291
Formula
C166H274N46O53S2
Molecular Weight
3826.40
CAS Number
90880-23-2
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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