Fig. 1 · Structure

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α-Hydroxyglutaric acid-d4 disodium

Stable Isotope

α-Hydroxyglutaric acid-d4 disodium is a stable isotope-labeled form of α-Hydroxyglutaric acid. This compound serves as a competitive inhibitor of various α-ketoglutarate-dependent dioxygenases, including histone demethylases and TET enzymes involved in 5-methylcytosine hydroxylation. Its unique labeling facilitates quantitative studies and metabolic tracing in research applications related to epigenetics and metabolism.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2483831-91-8
Applications Stable Isotope
Formula C5H2D4Na2O5
Molecular Weight 196.10
Synonyms 2-Hydroxyglutarate-d4 disodium; 2-Hydroxyglutaric acid-d4 disodium; 2-Hydroxypentanedioic acid-d4 disodium
SMILES
O=C(O[Na])CC([2H])([2H])C(O[2H])([2H])C(O[Na])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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