α-Lipoic Acid sodium is a potent antioxidant that serves as a crucial cofactor for mitochondrial enzyme complexes. It effectively inhibits NF-κB-dependent activation of the HIV-1 long terminal repeat (LTR) and induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. This compound can be utilized in conjunction with CPUL1 to form the self-assembled nanoaggregate CPUL1-LA NA, which demonstrates enhanced antitumor efficacy compared to CPUL1 alone.
α-Lipoic Acid sodium is a potent antioxidant that serves as a crucial cofactor for mitochondrial enzyme complexes. It effectively inhibits NF-κB-dependent activation of the HIV-1 long terminal repeat (LTR) and induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. This compound can be utilized in conjunction with CPUL1 to form the self-assembled nanoaggregate CPUL1-LA NA, which demonstrates enhanced antitumor efficacy compared to CPUL1 alone.
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