Fig. 1 · Structure

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α-MSH TFA

MC4R Agonist

α-MSH TFA is a potent agonist of the melanocortin receptor 4 (MC4R). This endogenous neuropeptide exhibits anti-inflammatory and antipyretic properties, making it valuable for research into metabolic regulation and neuroinflammatory responses. As a post-translational derivative of pro-opiomelanocortin (POMC), α-MSH TFA serves as an important tool for studying the physiological roles of melanocortins in various biological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 171869-93-5
Applications MC4R Agonist
Formula C77H109N21O19S.xC2HF3O2
Molecular Weight 1778.93
Synonyms α-Melanocyte-Stimulating Hormone TFA
SMILES
OC(=O)C(F)(F)F.CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O |@:119|

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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