Fig. 1 · Structure

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α-Neoendorphin (porcine)

Peptide

α-Neoendorphin (porcine) is a peptide that acts on the skin's cellular mechanisms to mitigate UVB-induced photoaging. It activates the mTOR-Beclin-1 pathway to enhance autophagy, decreases reactive oxygen species (ROS) production, inhibits the MAPK signaling pathway and matrix metalloproteinase (MMP) activity, while promoting synthesis of type I procollagen. This compound demonstrates significant anti-aging and anti-wrinkle properties in skin cell models, making it valuable for research focused on skin photoaging and age-related dermatological studies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 77739-20-9
Applications Peptide
Formula C60H89N15O13
Molecular Weight 1228.44

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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