Fig. 1 · Structure
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A17
Anti-NASH Agent
A17 is a bile acid analog that serves as an anti-non-alcoholic steatohepatitis (NASH) agent. It exhibits significant anti-inflammatory activity by reducing fatty acid uptake and promoting fatty acid oxidation through the inhibition of fatty acid translocase (Cd36) expression and the activation of AMPKα. A17 is suitable for research applications focused on NASH and related metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2568186-47-8 |
| Applications | Anti-NASH Agent |
| Formula | C31H51NO6 |
| Molecular Weight | 533.75 |
| SMILES | O=CO[C@@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCC(N[C@H](CO)C(C)C)=O)C)([H])[C@@]4([C@](C[C@@H](CC4)OC=O)([H])C1)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.