Fig. 1 · Structure
Documents & Downloads
α1A/1D-Adrenoceptor antagonist-1
α1A/1D-Adrenoceptor Antagonist
α1A/1D-Adrenoceptor antagonist-1 is a selective dual antagonist targeting the α1A and α1D-adrenoceptors, with IC50 values of 20.26 nM and 164.9 nM, respectively. This compound exhibits a significantly higher IC50 of 1912 nM for the α1B-adrenoceptor, indicating its specificity. α1A/1D-Adrenoceptor antagonist-1 is valuable in research applications related to benign prostatic hyperplasia, contributing to the understanding of therapeutic approaches for this condition.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1049442-53-6 |
| Applications | α1A/1D-Adrenoceptor Antagonist |
| Formula | C22H27N3O4 |
| Molecular Weight | 397.47 |
| SMILES | O=C(NCCCN1CCN(C2=CC=CC=C2OC)CC1)C3=CC(OCO4)=C4C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.