Fig. 1 · Structure
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A1AT modulator 1
Antitrypsin inhibtor
A1AT modulator 1 is a potent inhibitor of Z α1-antitrypsin polymerization, exhibiting a pIC50 value of 8.3. This compound plays a significant role in the regulation of α1-antitrypsin, which is crucial for protease inhibition and inflammation control. It is valuable for research applications focused on understanding and modulating protein misfolding and related diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2406205-61-4 |
| Applications | Antitrypsin inhibtor |
| Formula | C21H23FN2O3 |
| Molecular Weight | 370.42 |
| SMILES | O=C(C1=CC=CC2=C1CC(N2)=O)N[C@@H]([C@H](C3=CC=CC(F)=C3C)O)CCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.