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A85380

Nicotinic Acetylcholine Receptor Agonists

A85380 is a high-affinity agonist for neuronal nicotinic acetylcholine receptors (nAChRs), demonstrating selectivity for the α4β2 nAChR subtype. This compound has been shown to possess a broad-spectrum analgesic profile, making it valuable in pain research. Its distinct mechanism of action offers potential insights into the therapeutic applications of nAChR modulation in various neurological disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	161416-98-4
Applications	Nicotinic Acetylcholine Receptor Agonists
Formula	C₉H₁₂N₂O
Molecular Weight	164.20
SMILES	C1(OC[C@@H]2CCN2)=CN=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.