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AAG561

CRF1 Antagonist

AAG561 is a potent antagonist of the corticotropin-releasing factor receptor 1 (CRF1). This compound is instrumental in investigating the mechanisms behind emotion dysregulation associated with various mental disorders. AAG561's ability to modulate CRF1 activity makes it a valuable tool for research into stress-related behaviors and the neurobiology of anxiety and depression.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	235760-14-2
Applications	CRF1 Antagonist
Formula	C₂₂H₂₇ClN₆
Molecular Weight	410.94
Synonyms	NVP-AAG 561
SMILES	CC1=C(N(CCC)CC2CC2)N=C(C)N=C1NC(C3=NC=CN=C34)=C(Cl)C=C4C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.