Fig. 1 · Structure
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Abatacept
Immunomodulator
Abatacept is an immunomodulator that functions as a selective T-cell co-stimulation modulator. As a soluble fusion protein, it comprises the extracellular domain of human CTLA4 fused to a fragment of the Fc portion of human IgG1, specifically the hinge and CH2 and CH3 domains. Abatacept is primarily utilized in research focused on autoimmune diseases, aiding in the understanding of T-cell activation and regulatory mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 332348-12-6 |
| Applications | Immunomodulator |
| Molecular Weight | 84.4 kDa |
| Synonyms | CTLA4lg; BMS-188667 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.