Fig. 1 · Structure
Documents & Downloads
Abecarnil
BZ Receptor Agonist
Abecarnil is a partial agonist of the benzodiazepine (BZ) receptor, functioning primarily as a positive allosteric modulator of the GABAA receptor. It exhibits significant anxiolytic and anticonvulsant properties, making it valuable in neuroscience research. Abecarnil effectively inhibits the binding of the BZ [3H]lormetazepam to rat cerebral cortex membranes, with an IC50 of 0.82 nM, and is particularly useful in studies related to epilepsy.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Partial Agonist |
| CAS Number | 111841-85-1 |
| Applications | BZ Receptor Agonist |
| Formula | C24H24N2O4 |
| Molecular Weight | 404.46 |
| Synonyms | ZK 112119 |
| SMILES | O=C(C1=NC=C2NC3=C(C2=C1COC)C=C(OCC4=CC=CC=C4)C=C3)OC(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.