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Abetimus

Immunosuppressant

Abetimus is an immunosuppressant composed of four double-stranded DNA (dsDNA) oligonucleotides. It functions by crosslinking anti-dsDNA antibodies on the surface of B cells, thereby reducing the levels of these antibodies. This agent has significant potential for research applications in systemic lupus erythematosus, providing insights into the mechanisms underlying this autoimmune disorder.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	167362-48-3
Applications	Immunosuppressant
Formula	C₁₆₃₂H₂₁₀₀N₆₁₀O₉₇P₁₅₆S₄
Molecular Weight	50742.05
Synonyms	LJP 394 free base

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.