Fig. 1 · Structure
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ABR-238901
S100A8/A9 Blocker
ABR-238901 is a potent oral inhibitor of the S100A8/A9 complex, effectively blocking its interaction with receptors RAGE and TLR4. This compound demonstrates significant potential in research related to myocardial infarction (MI) and inflammation. By targeting the S100A8/A9 pathway, ABR-238901 may contribute to a better understanding of the mechanisms underlying cardiovascular diseases and the role of these damage-associated molecular patterns in inflammatory responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1638200-22-2 |
| Applications | S100A8/A9 Blocker |
| Formula | C11H9BrClN3O4S |
| Molecular Weight | 394.63 |
| SMILES | O=S(NC1=C(O)C(Cl)=CN=C1)(C2=CN=C(C(Br)=C2)OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.