Fig. 1 · Structure
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ABT-107
nAChR Agonist
ABT-107 is a selective agonist of the α7 neuronal nicotinic receptor (nAChR), known for its neuroprotective properties. This compound has demonstrated effectiveness in protecting against nigrostriatal damage in rodent models, specifically in rats with unilateral 6-hydroxydopamine lesions. ABT-107 is a valuable tool for research applications focusing on neurodegenerative diseases and the role of nicotinic receptors in neurological function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 855291-54-2 |
| Applications | nAChR Agonist |
| Formula | C19H20N4O |
| Molecular Weight | 320.39 |
| SMILES | [C@H]1(C2CCN(CC2)C1)OC3=CC=C(C4=CC=C(NC=C5)C5=C4)N=N3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.