Fig. 1 · Structure

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Ac-DEVDD-TPP

Antitumor agent

Ac-DEVDD-TPP is a porphyrin derivative that targets caspase-3 for selective activation. Upon cleavage by caspase-3 and exposure to laser irradiation, it generates D-TPP, which facilitates the formation of porphyrin nanofibers. These nanofibers promote both apoptosis and pyroptosis, exhibiting significant antitumor activity, making Ac-DEVDD-TPP a valuable tool for cancer research applications.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2950171-24-9
Applications Antitumor agent
Formula C68H64N10O14
Molecular Weight 1245.29

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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