Fig. 1 · Structure
Documents & Downloads
Ac-H-FluNox
Prodrug
Ac-H-FluNox is an acetylated prodrug that targets intracellular esterases for hydrolysis, leading to the release of H-FluNox. Once activated, H-FluNox engages in a deoxygenation reaction with labile heme, resulting in a fluorescent product. This reagent is valuable for detecting variations in labile heme levels within living cells, particularly during acute nitric oxide stimulation and following the inhibition of heme export proteins, making it a powerful tool for studying cellular heme dynamics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2897614-60-5 |
| Applications | Prodrug |
| Formula | C27H21F2NO6 |
| Molecular Weight | 493.46 |
| SMILES | O=C1OC2(C3=C1C=CC=C3)C4=CC=C(C=C4OC5=CC([N+]6(CCC(F)(CC6)F)[O-])=CC=C52)OC(C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.