Fig. 1 · Structure
Documents & Downloads
Ac-VLPE-FMK
Cat-B/L Inhibitor
Ac-VLPE-FMK is a tetrapeptidyl mono-fluoromethyl ketone (m-FMK) that selectively inhibits Cathepsin B (Cat-B) and Cathepsin L (Cat-L). This compound is essential for studying the role of these cysteine proteases in cancer progression and aggressiveness. Its inhibitory activity can facilitate investigations into the mechanisms by which Cat-B and Cat-L contribute to tumor biology and metastasis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2679825-27-3 |
| Applications | Cat-B/L Inhibitor |
| Formula | C25H41FN4O7 |
| Molecular Weight | 528.61 |
| Synonyms | Ac-Val-Leu-Pro-Glu(OMe)-CH2F |
| SMILES | O=C(N(CCC1)[C@@H]1C(N[C@H](C(CF)=O)CCC(OC)=O)=O)[C@H](CC(C)C)NC([C@H](C(C)C)NC(C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.