ACBI-4

Name: ACBI-4
Brand: Adooq Bioscience
SKU: A63560
Rating: 5 (288 reviews)

Catalog No.: A63560

KRAS(on) PROTAC Degrader

ACBI-4 is a selective PROTAC degrader targeting the active state of KRAS (KRAS(on)). This compound exhibits significant anti-proliferative effects and effectively degrades various KRAS mutants, including KRASG12R, in cancer cell models. ACBI-4 is valuable for research applications focused on understanding KRAS-mediated signaling pathways and developing targeted cancer therapies.

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ACBI-4 3097985-19-5 KRAS(on) PROTAC Degrader

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Grouped product items
Size	Price	Stock
1mg	$2,400.00	In stock
5mg	$6,150.00	In stock
10mg	$10,710.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	ACBI-4 is a selective PROTAC degrader targeting the active state of KRAS (KRAS(on)). This compound exhibits significant anti-proliferative effects and effectively degrades various KRAS mutants, including KRASG12R, in cancer cell models. ACBI-4 is valuable for research applications focused on understanding KRAS-mediated signaling pathways and developing targeted cancer therapies.

Product Information

Catalog Num	A63560
Formula	C50H63N15O4S
Molecular Weight	970.20
CAS Number	3097985-19-5
SMILES	CC([C@H](N1N=NC2=C1CC[C@H](CCCN3C[C@@H](N(CCC3)C4=NC(C5=NOC([C@@]6(C7=C(CCC6)SC(N)=C7C#N)C)=N5)=CC=N4)C)C2)C(N8C[C@@H](C[C@H]8C(NCC9=CC=C%10C(N(N=C%10)C)=C9)=O)O)=O)C

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