ACBI2

Name: ACBI2
Brand: Adooq Bioscience
SKU: A24688
Rating: 5 (288 reviews)

Catalog No.: A24688

SMARCA2 Degrader

ACBI2 is a potent VHL PROTAC designed for the targeted degradation of SMARCA2. With an EC50 of 7 nM and a DC50 of 1 nM in RKO cells, ACBI2 selectively modulates SMARCA2 levels, making it a valuable tool for studying SMARCA2-related pathways. This compound is particularly relevant in lung cancer research, facilitating investigations into therapeutic strategies targeting SMARCA2 degradation.

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Grouped product items
Size	Price	Stock
1mg	$240.00	In stock
5mg	$615.00	In stock
10mg	$1,010.00	In stock
25mg	$2,015.00	In stock
50mg	$3,150.00	In stock
100mg	$4,610.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Adooq Products cited in reputable paper

Biological Activity

Description	ACBI2 is a potent VHL PROTAC designed for the targeted degradation of SMARCA2. With an EC50 of 7 nM and a DC50 of 1 nM in RKO cells, ACBI2 selectively modulates SMARCA2 levels, making it a valuable tool for studying SMARCA2-related pathways. This compound is particularly relevant in lung cancer research, facilitating investigations into therapeutic strategies targeting SMARCA2 degradation.

Product Information

Catalog Num	A24688
Formula	C56H68BrFN8O5S
Molecular Weight	1064.16
CAS Number	2913161-19-8
SMILES	BrC1=CC=CC(N(C2=CC=C(C3CCN(CC[C@@H](C)CC[C@@H](C4=CC=C(C5=C(C)N=CS5)C=C4)NC([C@@H]6C[C@@H](O)CN6C([C@H](C(C)(C)C)NC(C7(CC7)F)=O)=O)=O)CC3)C=C2N8C9CCCC9)C8=N%10)=C1C%10=O

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