Fig. 1 · Structure
Documents & Downloads
ACC1/2-IN-1
ACC1/2 Inhibitor
ACC1/2-IN-1 is a potent inhibitor of acetyl-CoA carboxylase 1 and 2 (ACC1/2), demonstrating IC50 values of 98.06 nM and 29.43 nM for ACC1 and ACC2, respectively. This compound is valuable for cancer research, as it inhibits fatty acid synthesis, a process often upregulated in tumorigenesis. Researchers can utilize ACC1/2-IN-1 to explore metabolic pathways and investigate therapeutic strategies targeting ACC in cancer cells.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2350219-22-4 |
| Applications | ACC1/2 Inhibitor |
| Formula | C34H32N4O4 |
| Molecular Weight | 560.64 |
| SMILES | O=C(C1=C(O2)C=C3C(CCC(C)(C)O3)=C1)CC42CCN(C(C5=CC=C6NC(C7=CC8=C(NC=C8)C=C7)=NC6=C5)=O)CC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.