Fig. 1 · Structure
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ACC1/2-IN-2
ACC1/2 Inhibitor
ACC1/2-IN-2 is a potent inhibitor of acetyl-CoA carboxylases ACC1 and ACC2, displaying IC50 values of 22 nM and 48 nM, respectively. This compound exhibits significant antiproliferative activity, making it a valuable tool for cancer research. Its selective inhibition of ACC1 and ACC2 provides insights into cellular metabolism and potential therapeutic avenues for tumor growth regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1031411-94-5 |
| Applications | ACC1/2 Inhibitor |
| Formula | C24H25N3O3 |
| Molecular Weight | 403.47 |
| SMILES | O=C1CC2(CCN(C(C3=CC4=C(NN=C4)C(C)=C3)=O)CC2)OC5=CC(C)=C(C)C=C15 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.