Fig. 1 · Structure
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ACC1/2-IN-3
ACC1/2 Inhibitor
ACC1/2-IN-3 is a potent inhibitor of Acetyl-CoA Carboxylase 1 and 2 (ACC1/2), exhibiting an IC50 value between 1-10 nM for both targets. This compound is valuable for investigating diseases associated with ACC, particularly metabolic disorders. Its selective inhibition of ACC1 and ACC2 provides a useful tool for research into metabolic pathways and potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2131091-32-0 |
| Applications | ACC1/2 Inhibitor |
| Formula | C32H39N3O8S |
| Molecular Weight | 625.73 |
| SMILES | O=C(OC(C)(C)C)C(C)(C)N(C(N(C[C@@H](C1=CC=CC=C1OC)OC2CCOCC2)C3=C4C(C)=C(C5=NC=CO5)S3)=O)C4=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.