Fig. 1 · Structure

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ACC1-IN-2

ACC1 Inhibitor

ACC1-IN-2 is a selective inhibitor of acetyl-CoA carboxylase 1 (ACC1), exhibiting an IC50 of 7.3 nM. This compound is utilized in biological research to investigate the role of ACC1 in lipid metabolism and related disorders, including acne pathogenesis. Its potent inhibitory activity makes it a valuable tool for studying ACC1's impact on cellular processes and therapeutic approaches in dermatological research.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3027705-67-2
Applications ACC1 Inhibitor
Formula C27H30N2O2S
Molecular Weight 446.60
SMILES
CC1=C(C=CC=C2)C2=CC(C(N3CCC(CC4=O)(CC5=C4N=C(C(C)(C)C)S5)CC3)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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