ACDPP is a selective antagonist of the metabotropic glutamate receptor 5 (mGluR5). It effectively inhibits the elevation of fragile X mental retardation protein (FMRP) induced by DHPG, a group I mGluR agonist. ACDPP is utilized in research to investigate the role of mGluR5 signaling in neurodevelopmental disorders, particularly in the context of fragile X syndrome.
ACDPP is a selective antagonist of the metabotropic glutamate receptor 5 (mGluR5). It effectively inhibits the elevation of fragile X mental retardation protein (FMRP) induced by DHPG, a group I mGluR agonist. ACDPP is utilized in research to investigate the role of mGluR5 signaling in neurodevelopmental disorders, particularly in the context of fragile X syndrome.
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