Fig. 1 · Structure
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Aceglatone
Antineoplastic Agent
Aceglatone is an antineoplastic agent that functions as a β-glucuronidase inhibitor. This compound effectively reduces colon carcinogenesis by preventing the hydrolysis of glucuronides, thereby inhibiting the onset of colon cancer. Additionally, Aceglatone demonstrates the ability to decrease cell proliferation, induce apoptosis, and inhibit DNA synthesis in human colon cancer cells, making it a valuable tool for research in cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 642-83-1 |
| Applications | Antineoplastic Agent |
| Formula | C10H10O8 |
| Molecular Weight | 258.18 |
| SMILES | CC(O[C@H]1[C@]2([H])[C@@](OC1=O)([H])[C@H](C(O2)=O)OC(C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.