Fig. 1 · Structure
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Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27)
VIP1 Antagonist
Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27) is a vasoactive intestinal peptide (VIP) 1 antagonist. This compound effectively inhibits VIP-mediated signaling, thereby modulating physiological processes associated with gastrointestinal function and smooth muscle relaxation. It has significant potential for research applications in studying gastrointestinal disorders and the role of VIP in various pathophysiological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 202463-00-1 |
| Applications | VIP1 Antagonist |
| Formula | C150H246N44O38 |
| Molecular Weight | 3273.83 |
| SMILES | [C@H](CC1=CC=CC=C1)(NC([C@H](CC2=CN=CN2)NC(C)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)[C@H](CC)C)=O)CC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CC(C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)C)=O)CO)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCCN)=O)CC(C)C)=O)[C@@H](C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)=O)CO)=O)CC(N)=O)=O)[C@@H](C)O)=O)=O)C(C)C)=O)C)=O)CC(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.