Fig. 1 · Structure
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Acetylethylcholine mustard hydrochloride
Choline Acetyl-transferase Inhibitor
Acetylethylcholine mustard hydrochloride serves as an irreversible inhibitor of choline acetyl-transferase, effectively diminishing the synthesis of acetylcholine (ACh) with an IC50 value of 1.22 mM. This compound reduces myotube contraction frequency, making it valuable for studies on neuromuscular transmission and cholinergic signaling. Additionally, Acetylethylcholine mustard hydrochloride acts as a cholinotoxin and is a precursor to the ethylcholine mustard aziridinium ion, further enhancing its utility in chemical research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 103994-00-9 |
| Applications | Choline Acetyl-transferase Inhibitor |
| Formula | C8H17Cl2NO2 |
| Molecular Weight | 230.13 |
| Synonyms | Acetyl-AF64 |
| SMILES | CCN(CCOC(C)=O)CCCl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.