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Acrovestone

Anticancer Agent

Acrovestone is an Acronychia-type acetophenone dimer that functions as a selective anticancer agent. It demonstrates potent cytotoxicity with IC50 values of 0.38 μM against A2058 melanoma cells and 0.93 μM against DU145 prostate cancer cells, while exhibiting minimal inhibitory effects on normal human dermal fibroblasts (IC50 >5 μM). This compound is suitable for research applications targeting melanoma and prostate cancer, providing a foundation for investigating its therapeutic potential. Acrovestone can be naturally sourced from the trunk bark of Acronychia pedunculata.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	24177-16-0
Applications	Anticancer Agent
Formula	C₃₂H₄₂O₈
Molecular Weight	554.67
SMILES	O=C(C)C1=C(O)C(C(CC(C)C)C2=C(C(C(C)=O)=C(C(C/C=C(C)\C)=C2O)OC)O)=C(O)C(C/C=C(C)\C)=C1O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.