ACSS2-IN-1 is a highly effective inhibitor of ACSS2, demonstrating an IC50 of 0.01 nM to <1 nM. This compound offers significant potential for the exploration of cancer biology, particularly in studies focusing on metabolic pathways and therapeutic strategies. Its ability to modulate ACSS2 activity positions it as a valuable tool for researchers investigating cancer progression and treatment options.
Fig. 1 · Structure
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ACSS2-IN-1
ACSS2 Inhibitor
ACSS2-IN-1 is a highly effective inhibitor of ACSS2, demonstrating an IC50 of 0.01 nM to <1 nM. This compound offers significant potential for the exploration of cancer biology, particularly in studies focusing on metabolic pathways and therapeutic strategies. Its ability to modulate ACSS2 activity positions it as a valuable tool for researchers investigating cancer progression and treatment options.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2711039-08-4 |
| Applications | ACSS2 Inhibitor |
| Formula | C27H25ClN6O2 |
| Molecular Weight | 500.98 |
| SMILES | O=C(C1=CC2=C(CC)C(C(C3=CC=CC=C3)(C4=CC=CC=C4)O)=NN2C=C1Cl)NC5=NN(CC)C=N5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.