ACT-1004-1239

Catalog No.: A59769
CXCR Antagonist
ACT-1004-1239 is a selective antagonist of the CXCR7 receptor, exhibiting a potent inhibitory effect with an IC50 value of 3.2 nM. This compound is primarily utilized in research focused on chemokine signaling pathways and is relevant in studies investigating disorders related to the immune system and cancer. Its oral bioactivity makes it an attractive candidate for in vivo investigations targeting CXCR7-mediated pathways.
Grouped product items
Size Price Stock Qty
1mg
$170.00
In stock
5mg
$440.00
In stock
10mg
$730.00
In stock
25mg
$1,495.00
In stock
50mg
$2,345.00
In stock
100mg
$4,320.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionACT-1004-1239 is a selective antagonist of the CXCR7 receptor, exhibiting a potent inhibitory effect with an IC50 value of 3.2 nM. This compound is primarily utilized in research focused on chemokine signaling pathways and is relevant in studies investigating disorders related to the immune system and cancer. Its oral bioactivity makes it an attractive candidate for in vivo investigations targeting CXCR7-mediated pathways.
Product Information
Catalog NumA59769
FormulaC27H28F2N6O3
Molecular Weight522.55
CAS Number2178049-58-4
SMILESO=C([C@H]1CN(CC2CC2)CC[C@@H]1NC(C3=NOC(C4=CC=C(F)C=C4F)=C3)=O)NC5(C6=NC=CC=N6)CC5
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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