Fig. 1 · Structure
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ACT-678689
TPH Inhibitor
ACT-678689 is a potent inhibitor of tryptophan hydroxylase (TPH), exhibiting an IC50 value of 8 nM. This compound plays a critical role in the modulation of serotonin synthesis, making it valuable for research in neuropharmacology and the study of mood disorders. Its selective inhibition of TPH allows for in-depth investigation into serotonin-related pathways and their physiological implications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1783256-96-1 |
| Applications | TPH Inhibitor |
| Formula | C23H22ClFN6O4S2 |
| Molecular Weight | 565.04 |
| SMILES | CS(=O)(NC1=NC(Cl)=C(OCC(N2CCC3=C(N4C(SC(C)=N4)=N3)[C@@H]2C5=CC=C(C)C=C5F)=O)C=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.